[S573.Ebook] Download Michael Hedges; Rhythm, Sonority, Silence, by Michael Hedges, John Stropes

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This remarkable book is the culmination of an eight-year joint effort between Michael Hedges and John Stropes, a leading teacher and author of other critically acclaimed finger-style guitar books. "I first talked with Michael Hedges about working with him to produce a book of his music in 1986," said Stropes. "Our dream was to do it right. The challenge was to create a guitar book that would give the complete picture the composer's musical intent and a complete technical description for performers. It was clear that this would require an extended vocabulary for notation, expanded technologies for transcription and music typesetting and a new vision in music publishing." The transcriptions contained in Michael Hedges/Rhythm, Sonority, Silence were developed from videotapes of Michael Hedges recorded between 1983 and 1992. The videotapes were made at concerts, master classes, lectures, interviews and special sessions. These special sessions used three cameras (left-hand, right-hand and wide shot) running independent, time-coded tape. Working from these videotapes and using half-speed video and half-speed audio, a rough draft of a transcription was made. Then, discussions with Michael Hedges explicated the composer's intentions. Next, this revised draft of the transcription was compared with the original Windham Hill audio recording to arrive at an exact correspondence. Finally, the material was tested using intermediate and advanced students to ensure that the notation was clear and thorough, and study notes were added to clarify any remaining ambiguities. In addition to the music, this book includes a moving automusicalbiography interspersed with rare and historic photos, original essays on composition, electronics and tunings, a complete discography and tunings database for all of Michael's recorded works.

• Sales Rank: #902750 in Books
• Published on: 1995-01-01
• Original language: English
• Dimensions: 8.70" h x .50" w x 10.90" l, 1.10 pounds
• Binding: Spiral-bound
• 136 pages

Most helpful customer reviews

17 of 18 people found the following review helpful.
Great Music Book But Don't Buy this on Amazon!!!
By Raptor
I have this book and it is THE BEST most accurate way to learn Michael Hedges songs on the guitar short of taking guitar lessons from his ghost (RIP M.H.). But you can get this book on Stropes.com for $40, that's right, brand new for FORTY DOLLARS!!! Don't fall for the price gouging here, it is disgusting how much these merchants want to charge and they should be ashamed of their greedy selves. Don't fall for it!

Edited: Gave this 5 stars like I should have in the first place.

7 of 7 people found the following review helpful.
Go to Stropes dot com
By Andy
This is one of the most important publications focusing on guitar pedagogy of the 20th century. The book covers many aspects of Hedges' oeuvre in depth, from the gear he used on stage to the essentials of his intricate technique. Most importantly, the book is still in print and is available on the publishers website, brand new, for $40.

6 of 6 people found the following review helpful.
An essential for any Michael Hedges fan
By Paige Jeffries
I gave this book to my friend who plays classical guitar and has loved Michael Hedges for as long as I can remember. He wanted to start to learn to play some of Hedges' songs. This book is great, but difficult to pick up and play if this style is new to you. There is a DVD of Hedges in concert that I would recommend so that if/when you are having difficulty reading the sheet music, you can see Hedges playing it in front of you.

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[C781.Ebook] Ebook Drug Metabolism and Pharmacokinetics Quick Guide, by Siamak Cyrus Khojasteh, Harvey Wong, Cornelis E.C.A. Hop

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This Quick Guide covers aspects of drug assessment at the drug discovery and development stages, including pharmacokinetics, absorption, metabolism, enzyme kinetics, drug transporters, drug interactions, drug-like properties, assays and in silico calculations.

• Sales Rank: #1156084 in Books
• Published on: 2011-04-19
• Released on: 2011-04-19
• Original language: English
• Number of items: 1
• Dimensions: 8.00" h x .52" w x 5.00" l, .55 pounds
• Binding: Paperback
• 214 pages

Review

From the reviews:

“The authors have to be complimented with this comprehensive book of reference on various important topics in the field of pharmacokinetics and drug metabolism. It contains a large collection of figures and tables providing relevant and well-organized information. … In conclusion, this is a valuable reference for workers in the field of pharmacokinetics and drug metabolism, providing a storehouse of information in a comprehensive book.” (Johannes H. Proost, International Journal of Clinical Pharmacology and Therapeutics, Vol. 50 (6), June, 2012)

“The authors intend the book to inform important decisions in a timely fashion ‘for synthesis of superior compounds that have the potential for being a safe and effective drug’. The summary format was designed to be clear, concise and self-explanatory, so it could be used on a daily basis to inform those design decisions. It achieves this goal. It is intended for all drug-discovery scientists, and researchers in all disciplines will certainly find it useful. … In summary, this is a valuable little book.” (Andy Davis, ChemMedChem, Vol. 7, 2012)

“This guide can be used on a day-to-day basis as a useful reference for almost anyone, including students first learning these concepts, as well as scientists in the pharmaceutical industry hoping to apply these principles in their research. … This is a nicely organized quick reference on basic concepts in pharmacokinetics and drug metabolism. It will be a useful addition to the libraries of a variety of readers, from students in the pharmaceutical sciences to accomplished researchers in drug development.”­­­ (Melissa M. Ranieri, Doody's Book Reviews, December, 2011)

From the Back Cover

Drug Metabolism and Pharmacokinetics Quick Guide is intended for broad readership of those interested in the discipline of drug metabolism and pharmacokinetics who work in drug discovery coming from the various disciplines, a background such as of medicinal chemistry, pharmacology, drug metabolism and pharmacokinetics, bioanalysis, clinical sciences, biochemistry, pharmaceutics or toxicology.

This guide provides, for the first time, a completely integrated look at multiple aspects of absorption, distribution, metabolism, and excretion (ADME) science in a summary format that is clear, concise and self-explanatory.

This book will be used and referenced frequently as it provides detailed figures and tables for data interpretation. Also included are brief yet relevant factoids that bring a real-world dimension to the discussion of drug metabolism and pharmacokinetics.

Key topics covered:

1. Pharmacokinetics

2. Drug metabolizing enzymes

3. Oral absorption

4. Transporters

5. Metabolism-based drug interactions

6. Biotransformation and bioactivation

7. Prediction of human pharmacokinetics

8. Bioanalysis

9. Physicochemical properties and drug-like properties

10. In silico tools

11. Approved drugs

12. Chemical nomenclature

About the Author

Dr. Siamak Cyrus Khojasteh received his BS from University of California at Berkeley and his PhD from University of Washington in Medicinal Chemistry under the direction of Dr. Sidney D. Nelson.  Dr. Khojasteh leads the Metabolism efforts at Genentech (South San Francisco) and leads a team of about 20 scientists and prior to that he was a Senior Research Scientist at Pfizer (Groton, CT).  His research interest is mechanism of biotransformation particularly with formation of reactive metabolites by P450 or non-P450 enzymes.  

 

Harvey Wong graduated from the University of British Columbia with a Ph.D. in Pharmacokinetics and Biopharmaceutics.  Following graduation, he worked at the DuPont Pharmaceutics Company followed by Bristol-Myers Squibb in the area of Neuroscience Drug Discovery.  Currently, Harvey is a Senior Scientist in the Department of Drug Metabolism and Pharmacokinetics at Genentech, Inc. working in the areas of oncology and immunology.  He is involved in pharmacokinetic modeling and defining preclinical PK-PD relationships for drug candidates in both therapeutic areas. Harvey has published over 70 publications and abstracts.

 

Dr. Cornelis E.C.A. Hop is supervising the Small Molecule Drug Metabolism & Pharmacokinetics Department at Genentech (South San Francisco) and leads a team of about 55 scientists involved in acquisition and interpretation of ADME data in support of drug discovery and development.  Before that he was a senior director at Pfizer (Groton, CT) and a Senior Research Fellow at Merck (Rahway, NJ).  Dr. Hop has extensive experience in ADME sciences and biotransformation, PK prediction and bioanalysis in particular.  He has authored more than 100 publications in refereed journals and several book chapters and made more than 50 external oral presentations at conferences and universities.

Most helpful customer reviews

3 of 4 people found the following review helpful.
Great comprehensive and compact guide
By Amazon Customer
Wonderful guide, very useful as a quick reference or crash course in DMPK. Great coverage of important concepts, thoughtfully written an assembled, and easy to follow for those of us without formal training in pharmacokinetics.

0 of 0 people found the following review helpful.
Quick guide indeed
By nPe
If you wanted to get a start on DMPK, this is an awesome jumping off point. Accurate, current, easy to read and a convenient size for ready access. Wish there was an 'app' like this...

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Ian Thorpe's achievements in the water are nothing short of phenomenal. He has won a record-holding 11 World Championship titles and ten Commonwealth Games gold medals. He has broken 22 world records and won five gold, three silver and one bronze Olympic medals. Having been under the spotlight since he was a young teenager, Thorpe retired from competitive swimming in 2006 because of the intense pressure he felt, but five years later he decided to make a hugely publicized comeback. Ian is one of the world's most successful sportsmen, but it is the way he has managed his triumphs and his commitment to helping others that have earned him respect and admiration internationally. Thorpe's autobiography follows him all the way from his childhood in Sydney right up to the London Olympics. This is a man who has had highs and lows away from the pool, who has led an extraordinary life of an elite athlete that most of us will never know, who has faced up to his own demons, and who has the courage to come back and stake his claim for the ultimate goal once more.

• Sales Rank: #1190124 in Books
• Brand: Thorpe, Ian/ Wainwright, Robert
• Published on: 2012-10-01
• Original language: English
• Number of items: 1
• Dimensions: 1.10" h x 6.20" w x 9.30" l, 1.05 pounds
• Binding: Hardcover
• 336 pages

About the Author
Ian Thorpe is a world-famous freestyle swimmer. At the age of 14, he became the youngest male swimmer ever to represent Australia and the youngest ever individual male World Champion. He has won nine Olympic medals (five gold) and eleven World Championship golds.

Most helpful customer reviews

9 of 9 people found the following review helpful.
FYI, not a Tell-All but a wonderful book!
By Housefan2011
If you are in any way a fan of Ian Thorpe or swimming I would recommend this book. If you are looking for a juicy salacious tell-all, this is not it. Also, you cannot really read this without knowing anything about swimming or his career, but then I doubt you would be interested. However, if you are, just read his wiki page and that should be sufficient.

The book is organized in a diary format in the year leading up to the Olympics. Each entry starts in the present-day struggle to earn a spot on the Aussie Olympic team, and then it reverts back to past memories or his personal ideas or beliefs on issues. The flashbacks are not in chronological order which I suppose is true to how a person looks back on past events, but it can be a little confusing at times. It's easier to read if you take each chapter at a time and don't try to organize it in your head like I did. The transitions from the present day to past events made me keenly aware that this was written by two writers. I imagine Ian kept a diary, and then very separately wrote about past events and the professional writer put it all together and published it in three months. So, like so many books now, it was rushed, and while clearly very edited, there are some grammatical errors and a lack of fluidity. This is why it lost a star for me. Either keep it real and rough, the way a diary is written, or make it perfectly professional. This was very much in between the two.

I will say the honesty throughout is really refreshing. You get a very good sense of what it must have been like to be a a champion at such a young age and the pressures he has lived with all these years and again with his comeback. He clearly is a very sensitive and private person and, as a long-time fan, this is his most revealing project. This might be the first time we get a real sense of who he his. The problem, of course, is he still is that private person. Unlike many other athletes's memoirs, some private issues are addressed but still glazed over or kept vague. I am not really holding the book against it, but it's important to know if you read a lot of autobiographies. I would not call it a tell-all. The exception I would say is the now famous excerpt on depression. This was very raw and honest and deserves the attention it is receiving.

~The following is truly personal opinion that did not factor into my review.

He's gets annoyed but not angry, happy but not overjoyed. The anxiety seems to be the strongest emotion he feels in his comeback, and overall I was left with a feeling of sadness, which I can't completely explain. It is extremely rare that a very shy, sensitive person would become a famous athlete. This I think it what made him and continues to make him so interesting. However, those personality traits are disastrous combined with massive media attention and scrutiny. You receive a huge sense of this in the book. We are told he found the joy in swimming again, but there is not a lot of joy in this book. There is clearly still a Part II to his life which he hasn't even begun, and I hope he finds more happiness there.

3 of 3 people found the following review helpful.
Fascinating read
By busissi
I was very moved by Ian's totally honest and up front description of his life. A man with great depth and an ambition to help others less fortunate. You don't have to agree with everything but I admire his commitment to the things he believes in.

2 of 2 people found the following review helpful.
Awesome
By Michael Chiller
Ian Thorpe is a champion. This comment is not restricted to just his swimming. He is a champion because he cares about being a human being. He cares about good old fashioned values. Therefore he represents to me what Australia is all about. Opportunites that can be taken to acheive something great. Great read.

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In the early heydays of the second revolution of origami Tom Stamm, a devoted fan and practitioner of origami design, went through a rich period of exploration and creativity in the development of origami Dragons. Including his wonderful “Sea Serpent Dragon” and “Multi-Piece Sea Serpent” as well as 3 wonderful “Flapping Dragon” variations.



For the first time the most memorable of these are published here with loving re-diagramming as well as two small works of my own which were inspired during the redesign. I loved these models as a kid and am thrilled to be a part of making them available again. – JC Nolan

• Sales Rank: #151252 in eBooks
• Published on: 2015-03-28
• Released on: 2015-03-28
• Format: Kindle eBook

Most helpful customer reviews

3 of 3 people found the following review helpful.
Good Designs, Horrid Editing/Proofing
By R. Kronvold
Designs are interesting and different enough. In the paperback version I have there is the additional added puzzle of figuring out what order the steps are actually supposed to be in. Not sure if the Kindle version has the same issues. For instance the step order on the 2nd diagram (Sea Serpent Dragon) should actually be 1-6,19, 18, 17, 16, 15, 14, 13, 12, 11, repeat 18-11 on other side, 10, 9, 8, 7, then 20-58 in the printed order. Other than the horrible editing making a challenge, the designs are mostly intermediate level and are more for the interesting results and not to challenge the folder.

3 of 3 people found the following review helpful.
COOL
By Kay Kay
This book is full of amazing little oragami dragons that are really fun. I made one myself, it was a kinda hard, but I managed to do it with a little help from Dad.:)

1 of 1 people found the following review helpful.
Five Stars
By Robert
If you want to learn how to fold a dragon, this is the book to get.

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[I223.Ebook] PDF Download Tibetan Medicine: Illustrated in Original TextsFrom University of California Press

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History of Tibetam medicine with diagrams.

• Sales Rank: #2113607 in Books
• Published on: 1976-07-20
• Original language: English
• Number of items: 1
• Dimensions: 9.25" h x 6.50" w x 1.00" l,
• Binding: Paperback
• 346 pages

Most helpful customer reviews

3 of 4 people found the following review helpful.
Fantastic Purchase
By C. Miriam
I'm studying tibetan medicine, and I've found this text very useful. Also contains the biography of Yuthok Yonten Gonpo. I'm very satisfied with the purchase and with the seller. The book was in perfect conditions even when is a used one and just for 3 dollars.

0 of 0 people found the following review helpful.
Three Stars
By maria
Detailed history of Tibetam medicine with
Important diagrams.

0 of 0 people found the following review helpful.
Five Stars
By Isabelle Girardot
very good

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• Sales Rank: #4346618 in Books
• Brand: Brand: The Midnight Call
• Published on: 1984
• Number of items: 1
• Binding: Paperback
• 90 pages

Features

• Used Book in Good Condition

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